One person was injured shortly after midnight following a collision between a car and a motorbike in Noetrange.
Emergency services from Ettelbruck, Wiltz and Winseler arrived on the scene to help.
Another motorist was injured between Clervaux and Eselborn at 10.45pm, after their vehicle came off the road and struck a tree.
In Echternach, a factory caught fire on Rue Benedikt Zender shortly before 1am, requiring intervention from Echternach, Consdorf and Osweiler fire fighters. The incident caused material damage only.
